Annals of theICRP ICRP PUBLICATION 92 RelativeBiologicalEffectiveness(RBE) QualityFactor(Q) andRadiation WeightingFactor(wR) Editor J. VALENTIN PUBLISHED FOR The International Commission on Radiological Protection by PERGAMON
CONTENTS GUESTEDITORIAL PREFACE. 5 ABSTRACT. 7 1. INTRODUCTION 9 2. THE CONCEPT OF RBE RELATIVE BIOLOGICAL EFFECTIVENESS 13 2.1. Background. 13 2.2. Reference radiation.... 14 2.3. Different uses of the concept of RBE 24 3. QUANTIFICATION OF RBE 31 3.1. Two approaches to the determination of RBE 31 3.2. The use of life shortening in the determination of RBEm 34 3.3. Neutrons. 39 3.4. Protons. 47 3.5.α particles. 50 3.6. Heavy ions. 57 4. WEIGHTING FACTORS FOR RADIATION QUALITY. 63 4.1. Issues relating to the concepts of wg and Q 4.2. Effective dose: field or receptor quantity?. 64 69 4.3. Neutrons... 71 4.4. Options for a modified convention 75 5. DETERMINISTIC EFFECTS. 85 5.1. Introduction. 85 5.2.ICRP Publication 58 87 5.3. RBE for lens opacifications and cataracts 93 5.4. Non-cancer late effects. 95 6. CONCLUSIONS 97 6.1. Problems with the concept of RBE. 97 6.2. Need to invoke experimental data 97 6.3. Two approaches towards the determination of RBE- 98 6.4. Other uses of RBE. 99 6.5. Radiation weighting factor and quality factorconceptual problems. 100 6.6. Proposed convention for neutrons... 102 6.7. Proposed convention for heavy ions... 105 6.8. Radiation weighting for deterministic effects. 106 7. REFERENCES 109
GR PERGAMON ICRP Publication 92 Annals of the ICRP Guest Editorial ACURRENTVIEWONRADIATION WEIGHTINGFACTORSAND EFFECTIVE DOSE The International Commission on Radiological Protection (ICRP) developed radiation weighting factors (wg) for use in radiological protection in Publication 60 (ICRP 1991) and Table 1 includes the wg values that were remended. Since 1990 there have been substantial developments in biological and dosimetric knowl- edge that justify a re-appraisal of wg values and how they may be derived. This re- appraisal is the principal objective of the present report (Publicatior 92) which was a joint venture between ICRP Committees 1 and 2. This report is one of a set of documents being developed by ICRP Committees in order to advise the ICRP on the formulation of its next Remendations for Radiological Protection. Here we summarise our personal views on the principal implications of the report and how the ICRP might proceed with the derivation of wg values ahead of its forthing remendations. Table 1 provides a par- ison of wg values from Publication 60 with values proposed in the present report. In Pubficarion 60 the ICRP defined effective dose as the doubly weighted sum of absorbed dose in all the organs and tissues of the body. Dose limits are set in terms Table 1. A parison of existing wg values and those proposed to the ICRP Type and energy range of incident radiation Radiation weighting factor (wg) Pubficariow 60 Proposed Photons all energies Electrons and muons (all energies)a 1 1 Protons (incident) 5 1 Neutrons enengy100 keV2 MeV 20 >2 MeV20 MeV 10 Alpha particles fission fragments and heavy ionsb >20 MeV 5 20 Use Q-LET relationships of Ptn 60 forunsecifid partics. Exclude Auger eleetrons from emitters localising to cell nucleus/DNA- special treatment needed. Changes for neutron energies 200 keV/μm.
ICRP 92 Annals of the ICRP.pdf
